This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs [SKP1-cullin-F-box], which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes [BLAST Evalue to experimental molecule = 1.00e-300]
| Interaction ID | Total Unique Proteins in Interaction | MI Score |
|---|---|---|
| 1208502 | 3 | n/c |
| 631884 | 4 | 1.00 |
| 1208977 | 35 | 0.43 |
| 686400 | 4 | 0.99 |
| 714017 | 8 | 0.94 |
| 751279 | 4 | 1.00 |
| 767838 | 6 | 0.92 |
| 824298 | 3 | 1.00 |
| 829049 | 3 | 0.28 |
| 878045 | 8 | 0.89 |
| 1222125 | 87 | n/c |
| 900503 | 4 | 0.84 |
| 1224602 | 5 | 0.55 |
| 942833 | 3 | 0.54 |
| 1225439 | 55 | 0.43 |
| 960120 | 3 | 0.80 |
| 978977 | 5 | n/c |
| 980258 | 3 | 1.00 |
| 990177 | 3 | 0.99 |
| 1001689 | 9 | 0.55 |
| 1228674 | 17 | n/c |
| 1014037 | 7 | 0.83 |
| 1050671 | 10 | 0.43 |
| 1052994 | 5 | 1.00 |
| Interaction ID | # of Protein Repeats | MI Score |
|---|---|---|
| 1128174 | 2 | n/c |
| Name Space | Alias |
|---|---|
| dbj | BAB87200.1 |
| ensembl | ENSG00000145604 |
| entrezgene | 6502 |
| gb | AAK31593.1 |
| gb | EAW55936.1 |
| gb | EAW55938.1 |
| gi | 16306595 |
| grid | 112393 |
| hgnc | 10901 |
| hprd | {1} |
| hprd | {1} |
| interpro | IPR001810 |
| interpro | IPR022364 |
| omim | 601436 |
| pdb | 1FQV |
| pdb | 1FS1 |
| pdb | 1FS2 |
| pdb | 1LDK |
| pdb | 2ASS |
| pdb | 2AST |
| refseq | 6502 |
| refseq | NP_005974 |
| refseq | NP_005974.2 |
| refseq | NP_116026 |
| refseq | NP_116026.1 |
| uniprot | A8K5E0 |
| uniprot | Q13309 |
| uniprot | Q13309-2 |
| uniprot | Q8TDZ0 |
| uniprot | Q8TDZ1 |
| uniprot | Q9BV69 |