CCND1_HUMAN P24385 - Homo sapiens - iRefWeb - Wodak Lab

CCND1_HUMAN — P24385 — Homo sapiens

Parathyroid Adenomatosis 1; B-cell CLL/lymphoma 1; G1/S-specific cyclin D1. Forms a complex with and functions as a regulatory subunit of CDK4 or CDK6; required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene are observed in a variety of tumors and may contribute to tumorigenesis. This is a modelled interaction record. Any GIs listed below refer to the molecules being modelled, not to the molecules that were actually s

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